Detroit Tigers vs
Los Angeles DodgersPredictions & Preview

Dodgers Favored to Win Interleague Matchup Against Tigers in 2025 MLB Season Opener

The 2025 MLB season kicks off on Friday, March 28, with nine games across the league, including an interleague matchup at Dodger Stadium in Los Angeles between the Tigers and Dodgers. The first pitch is scheduled for 10:10 PM ET. Detroit and Los Angeles started a three-game series on Thursday night, with the results pending at the time of publication. In this article, we provide a prediction for the Tigers vs. Dodgers game on Friday night, featuring starting pitchers Jack Flaherty and Yoshinobu Yamamoto. The Dodgers are favored to win, with the betting line opening at -195 and currently at Los Angeles -200. Be sure to check out all of our MLB picks for the upcoming season.

Betting Odds

• Moneyline: Tigers +180 | Dodgers -200
• Spread: Tigers +1.5 (-120) | Dodgers -1.5 (+100)
• Total: Over/Under 7 (-110)
• Based on the moneyline, the implied probability that Los Angeles will win straight-up is 67%.

Detroit vs Los Angeles Stats

Detroit Tigers

The Detroit Tigers secured a spot in the 2024 playoffs primarily due to their strong pitching staff, which ranked fifth in runs allowed and posted the third-lowest ERA in the league. Despite ranking low in offensive statistics, such as runs scored and home runs, the team will need to rely more on their offense in the upcoming games. Jack Flaherty, a key pitcher for the Tigers, had a successful 2024 season and signed a two-year contract with the team in the offseason. With a power ranking of 5, the Tigers are ranked 0 in offense and defense and are currently 0-0 in the season.

Los Angeles Dodgers Analysis

The Los Angeles Dodgers have started their 2025 campaign strong with two wins over the Chicago Cubs in the MLB World Tour Tokyo Series, led by strong performances from Will Smith and Yoshinobu Yamamoto. Smith recorded two hits and five walks in the series, while Yamamoto earned a victory in his start, allowing only one earned run. The Dodgers bullpen also impressed with a 1.80 ERA and 0.43 FIP across 10 innings. Yamamoto will next face the Tigers on Friday, looking to build on his successful rookie season. The Dodgers currently hold the top power ranking in the league, ranking first in both offense and defense, with a perfect 2-0 record. Detroit has struggled against Los Angeles in previous matchups, going 1-2 in their last three meetings.

Los Angeles Dodgers Expected to Maintain Dominance in Upcoming Season, Pose Challenge for Jack Flaherty

During the previous season, the Los Angeles Dodgers demonstrated their strength by ranking second in the league for runs scored, third for home runs, and first for OPS. With a formidable lineup, it is anticipated that the Dodgers will maintain their dominance in the upcoming season. The Dodgers have a history of success against Jack Flaherty, boasting a 19-for-70 record with two doubles and four home runs against the pitcher. Flaherty will face a challenging task in trying to contain the Dodgers' potent offense. Noteworthy performances to watch for include Freddie Freeman's 7-for-19 record against Flaherty and Michael Conforto's 4-for-6 record. Despite missing key relievers, the Dodgers bullpen has proven effective against the Chicago Cubs. Therefore, it is recommended to consider the Dodgers at the runline for this matchup.

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