| Score | Moneyline | Spread | Game total | |
|---|---|---|---|---|
| Indianapolis ColtsIND | 22 | +135 L | +3 (-112) L | O 41.5 (-110) W U 41.5 (-105) L |
| Pittsburgh SteelersPIT | 34 | -155 W | -3 (-108) W |
Pittsburgh Steelers defeated Indianapolis Colts 34-22
Pittsburgh Steelers defeated Indianapolis Colts 34-22 on October 11, 2026, a 12-point decision in the series. Pittsburgh Steelers' strongest period was the 4th quarter, when it outscored its opponent 10-3. Against SportsJaw's recorded Indianapolis Colts +3 (-112) spread, Pittsburgh Steelers covered, while the 56 combined points finished over the recorded total of 41.5.
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