| Score | Moneyline | Spread | Game total | |
|---|---|---|---|---|
| Northern Illinois HuskiesNIU | 10 | +1096 L | +24 (-110) L | O 48.5 (-110) L U 48.5 (-110) W |
| Mississippi St. BulldogsMIS.ST | 38 | -2200 W | -24 (-110) W |
Mississippi St. Bulldogs defeated Northern Illinois Huskies 38-10
Mississippi St. Bulldogs defeated Northern Illinois Huskies 38-10 on September 20, 2025, a 28-point decision in the series. Mississippi St. Bulldogs' strongest period was the 4th quarter, when it outscored its opponent 14-0. Against SportsJaw's recorded Northern Illinois Huskies +24 (-110) spread, Mississippi St. Bulldogs covered, while the 48 combined points finished under the recorded total of 48.5.

