| Score | Moneyline | Spread | Game total | |
|---|---|---|---|---|
| Illinois Fighting IlliniILLINO | 10 | +210 L | +7 (-110) L | O 51.5 (-110) W U 51.5 (-110) L |
| Indiana HoosiersINDIAN | 63 | -260 W | -7 (-110) W |
Indiana Hoosiers defeated Illinois Fighting Illini 63-10
Indiana Hoosiers defeated Illinois Fighting Illini 63-10 on September 20, 2025, a 53-point decision in the series. Indiana Hoosiers' strongest period was the 2nd quarter, when it outscored its opponent 21-3. Against SportsJaw's recorded Illinois Fighting Illini +7 (-110) spread, Indiana Hoosiers covered, while the 73 combined points finished over the recorded total of 51.5.


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