Louisville Cardinals versus Syracuse Orange Head-to-head history

Scores, recaps and recorded betting results from the five most recent meetings in SportsJaw history.

SportsJaw’s stored game records date back to 2015. The news feed shows up to the five most recent completed meetings.

Head-to-head history

Last five meetings

Recent game recaps, recorded odds and betting results

Oct 17, 2026	Score	Moneyline	Spread	Game total
Louisville CardinalsLOUISV	34	-650 W	-14.5 (-110) L	O 57 (-110) W U 57 (-110) L
Syracuse OrangeSYR	26	+470 L	+14.5 (-110) W	O 57 (-110) W U 57 (-110) L

Louisville Cardinals defeated Syracuse Orange 34-26

Louisville Cardinals defeated Syracuse Orange 34-26 on October 17, 2026, a 8-point decision in the series. Louisville Cardinals' strongest period was the 1st quarter, when it outscored its opponent 14-10. Against SportsJaw's recorded Louisville Cardinals -14.5 (-110) spread, Syracuse Orange covered, while the 60 combined points finished over the recorded total of 57.

Team	1	2	3	4	T
Louisville Cardinals	14	14	0	6	34
Syracuse Orange	10	13	0	3	26

Sept 3, 2022	Score	Moneyline	Spread	Game total
Louisville CardinalsLOUISV	7	-198 L	-5.5 (-110) L	O 55.5 (-110) L U 55.5 (-110) W
Syracuse OrangeSYR	31	+170 W	+5.5 (-110) W	O 55.5 (-110) L U 55.5 (-110) W

Syracuse Orange defeated Louisville Cardinals 31-7

Team	1	2	3	4	T
Louisville Cardinals	7	0	0	0	7
Syracuse Orange	10	7	0	14	31

Nov 13, 2021	Score	Moneyline	Spread	Game total
Syracuse OrangeSYR	3	+140 L	+3 (-110) L	O 55.5 (-110) L U 55.5 (-110) W
Louisville CardinalsLOUISV	41	-165 W	-3 (-110) W	O 55.5 (-110) L U 55.5 (-110) W

Louisville Cardinals defeated Syracuse Orange 41-3

Team	1	2	3	4	T
Syracuse Orange	3	0	0	0	3
Louisville Cardinals	14	21	3	3	41

Nov 20, 2020	Score	Moneyline	Spread	Game total
Syracuse OrangeSYR	0	+650 L	+20.5 (-110) L	O 56 (-110) L U 56 (-110) W
Louisville CardinalsLOUISV	30	-1000 W	-20.5 (-110) W	O 56 (-110) L U 56 (-110) W

Nov 23, 2019	Score	Moneyline	Spread	Game total
Syracuse OrangeSYR	34	+245 L	+7.5 (-110) L	O 64.25 (-110) W U 64.25 (-110) L
Louisville CardinalsLOUISV	56	-290 W	-7.5 (-110) W	O 64.25 (-110) W U 64.25 (-110) L