Louisville Cardinals versus Pittsburgh Panthers Head-to-head history

Scores, recaps and recorded betting results from the five most recent meetings in SportsJaw history.

SportsJaw’s stored game records date back to 2015. The news feed shows up to the five most recent completed meetings.

Head-to-head history

Last five meetings

Recent game recaps, recorded odds and betting results

Sept 27, 2025	Score	Moneyline	Spread	Game total
Louisville CardinalsLOUISV	34	-150 W	-3 (-110) W	O 54.5 (-110) W U 54.5 (-110) L
Pittsburgh PanthersPITT	27	+130 L	+3 (-110) L	O 54.5 (-110) W U 54.5 (-110) L

Louisville Cardinals defeated Pittsburgh Panthers 34-27

Louisville Cardinals defeated Pittsburgh Panthers 34-27 on September 27, 2025, a 7-point decision in the series. Louisville Cardinals' strongest period was the 4th quarter, when it outscored its opponent 14-0. Against SportsJaw's recorded Louisville Cardinals -3 (-110) spread, Louisville Cardinals covered, while the 61 combined points finished over the recorded total of 54.5.

Team	1	2	3	4	T
Louisville Cardinals	0	17	3	14	34
Pittsburgh Panthers	17	10	0	0	27

Nov 23, 2024	Score	Moneyline	Spread	Game total
Pittsburgh PanthersPITT	9	+230 L	+7.5 (-110) L	O 57 (-110) L U 57 (-110) W
Louisville CardinalsLOUISV	37	-275 W	-7.5 (-110) W	O 57 (-110) L U 57 (-110) W

Louisville Cardinals defeated Pittsburgh Panthers 37-9

Team	1	2	3	4	T
Pittsburgh Panthers	0	0	7	2	9
Louisville Cardinals	10	17	10	0	37

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Oct 14, 2023	Score	Moneyline	Spread	Game total
Louisville CardinalsLOUISV	21	-285 L	-7 (-110) L	O 45 (-110) W U 45 (-110) L
Pittsburgh PanthersPITT	38	+235 W	+7 (-110) W	O 45 (-110) W U 45 (-110) L

Pittsburgh Panthers defeated Louisville Cardinals 38-21

Team	1	2	3	4	T
Louisville Cardinals	7	14	0	0	21
Pittsburgh Panthers	7	7	17	7	38

Oct 22, 2022	Score	Moneyline	Spread	Game total
Pittsburgh PanthersPITT	10	+105 L	+1.5 (-110) L	O 55 (-110) L U 55 (-110) W
Louisville CardinalsLOUISV	24	-125 W	-1.5 (-110) W	O 55 (-110) L U 55 (-110) W

Sept 26, 2020	Score	Moneyline	Spread	Game total
Louisville CardinalsLOUISV	20	+120 L	+3 (-110) P	O 54 (-110) L U 54 (-110) W
Pittsburgh PanthersPITT	23	-140 W	-3 (-110) P	O 54 (-110) L U 54 (-110) W

Verified performance

Experts who know these teams

Weighted grade based on 75% profit from head-to-head bets and 25% from profits earned betting on either team.

OddssharkWeighted grade35-$128 · 7 picks3–4 W–L · 42.9%2

1118240754Weighted grade34+$809 · 2 picks1–1 W–L · 50.0%3

KrockpicksWeighted grade32+$1,818 · 2 picks2–0 W–L · 100.0%

RankHandicapperGradeProfit

Original articles

Louisville Cardinals vs Pittsburgh Panthers preview archive

Pittsburgh Panthers vs Louisville CardinalsNov 23, 2024

Expert grades weight verified head-to-head profit at 75% and profit on other games involving either team at 25%, with a confidence adjustment until ten qualifying picks are recorded.