| Score | Moneyline | Spread | Game total | |
|---|---|---|---|---|
| Syracuse OrangeSYR | 64 | +450 L | +10 (-110) L | O 145.5 (-110) W U 145.5 (-110) L |
| Iowa St. CyclonesIOWAS | 95 | -625 W | -10 (-110) W |
Iowa St. Cyclones defeated Syracuse Orange 95-64
Iowa St. Cyclones defeated Syracuse Orange 95-64 on November 26, 2025, a 31-point decision in the series. Iowa St. Cyclones' strongest period was the 2nd half, when it outscored its opponent 60-30. Against SportsJaw's recorded Syracuse Orange +10 (-110) spread, Iowa St. Cyclones covered, while the 159 combined points finished over the recorded total of 145.5.
| Team | 1 | 2 | T |
|---|---|---|---|
| Syracuse Orange | 34 | 30 | 64 |
| Iowa St. Cyclones | 35 | 60 | 95 |

