| Score | Moneyline | Spread | Game total | |
|---|---|---|---|---|
| Iowa St. CyclonesIOWAS | 81 | +170 W | +4.5 (-110) W | O 154.5 (-110) L U 154.5 (-110) W |
| Purdue BoilermakersPURDU | 58 | -208 L | -4.5 (-110) L |
Iowa St. Cyclones defeated Purdue Boilermakers 81-58
Iowa St. Cyclones defeated Purdue Boilermakers 81-58 on December 6, 2025, a 23-point decision in the series. Iowa St. Cyclones' strongest period was the 2nd half, when it outscored its opponent 46-27. Against SportsJaw's recorded Iowa St. Cyclones +4.5 (-110) spread, Iowa St. Cyclones covered, while the 139 combined points finished under the recorded total of 154.5.