Clemson Tigers versus Louisville Cardinals Head-to-head history

Feb 28, 2026	Score	Moneyline	Spread	Game total
Louisville CardinalsLOUIS	75	-133 L	-2 (-110) L	O 147 (-110) W U 147 (-110) L
Clemson TigersCLEMS	80	+109 W	+2 (-110) W

Clemson Tigers defeated Louisville Cardinals 80-75

Clemson Tigers defeated Louisville Cardinals 80-75 on February 28, 2026, a 5-point decision in the series. Clemson Tigers' strongest period was the 1st half, when it outscored its opponent 38-35. Against SportsJaw's recorded Louisville Cardinals -2 (-110) spread, Clemson Tigers covered, while the 155 combined points finished over the recorded total of 147.

Jan 7, 2025	Score	Moneyline	Spread	Game total
Clemson TigersCLEMS	64	+138 L	+3.5 (-110) L	O 146.5 (-110) L U 146.5 (-110) W
Louisville CardinalsLOUIS	74	-164 W	-3.5 (-110) W

Louisville Cardinals defeated Clemson Tigers 74-64

Louisville Cardinals defeated Clemson Tigers 74-64 on January 7, 2025, a 10-point decision in the series. Louisville Cardinals' strongest period was the 1st half, when it outscored its opponent 42-35. Against SportsJaw's recorded Clemson Tigers +3.5 (-110) spread, Louisville Cardinals covered, while the 138 combined points finished under the recorded total of 146.5.

Jan 30, 2024	Score	Moneyline	Spread	Game total
Louisville CardinalsLOUIS	64	+900 L	+16 (-110) W	O 149.5 (-110) L U 149.5 (-110) W
Clemson TigersCLEMS	70	-1600 W	-16 (-110) L

Clemson Tigers defeated Louisville Cardinals 70-64