| Score | Moneyline | Spread | Game total | |
|---|---|---|---|---|
| Eastern Illinois PanthersE.ILL | 53 | +3300 L | +44 (-110) W | O 145.25 (-110) L U 145.25 (-110) W |
| Iowa St. CyclonesIOWAS | 78 | -10000 W | -44 (-110) L |
Iowa St. Cyclones defeated Eastern Illinois Panthers 78-53
Iowa St. Cyclones defeated Eastern Illinois Panthers 78-53 on December 14, 2025, a 25-point decision in the series. Iowa St. Cyclones' strongest period was the 1st half, when it outscored its opponent 44-28. Against SportsJaw's recorded Eastern Illinois Panthers +44 (-110) spread, Eastern Illinois Panthers covered, while the 131 combined points finished under the recorded total of 145.25.
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