| Score | Moneyline | Spread | Game total | |
|---|---|---|---|---|
| Notre Dame Fighting IrishND | 56 | +560 L | +11.5 (-110) W | O 133 (-110) L U 133 (-110) W |
| Houston CougarsHOUST | 66 | -825 W | -11.5 (-110) L |
Houston Cougars defeated Notre Dame Fighting Irish 66-56
Houston Cougars defeated Notre Dame Fighting Irish 66-56 on November 26, 2025, a 10-point decision in the series. Houston Cougars' strongest period was the 1st half, when it outscored its opponent 39-25. Against SportsJaw's recorded Notre Dame Fighting Irish +11.5 (-110) spread, Notre Dame Fighting Irish covered, while the 122 combined points finished under the recorded total of 133.


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