MLB Picks

MLB Previews & Predictions

Today

4/22/2025

Free mlb picks, staff preview, prediction, best bets, and more. Your #1 source for the best MLB Picks every day. Looking for expert MLB picks? Checkout today's MLB best bets from MLB experts.

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Today's MLB Picks

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Dodgers and Cubs set to face off in pivotal two-game series at Wrigley Field as pitching matchup heats up

MLB

Los Angeles 10

Chicago 9

LIVEMid 9th

Pittsburgh Pirates to Face Los Angeles Angels in Three-Game Series, Angels Favored to Win Game 1

MLB

Pittsburgh 5

Los Angeles 1

LIVETop 4th

Tampa Bay Rays Look to Extend Winning Streak Against Arizona Diamondbacks in MLB Showdown

MLB

Tampa Bay 1

Arizona 2

LIVEMid 4th

Brewers Look to Extend Winning Streak Against Giants in NL Playoff Preview Game

MLB

Milwaukee 3

San Francisco 1

LIVETop 4th

Oakland Athletics Favored Over Texas Rangers in Opener of Three-Game Series, Patrick Corbin's Struggles Raise Doubts

MLB

Texas 3

Oakland 1

LIVETop 3rd

Yankees Set to Face Off Against Guardians in Exciting Matchup: New York Poised for Victory?

MLB

New York 2

Cleveland 3

4/22/2025FINAL

Cincinnati Reds Poised for Victory Against Struggling Miami Marlins in Middle Game of Series

MLB

Cincinnati 3

Miami 4

4/22/2025FINAL

San Diego Padres to Face Detroit Tigers in Battle of Division Leaders at Comerica Park on April 22, 2025

MLB

San Diego 2

Detroit 0

4/22/2025FINAL

Seattle Mariners Gear Up to Face Boston Red Sox in Crucial Three-Game Series at Fenway Park

MLB

Seattle 3

Boston 8

4/22/2025FINAL

Baltimore Orioles and Washington Nationals Set to Clash in Three-Game Series at Nationals Park, Both Teams Looking for Redemption

MLB

Baltimore 0

Washington 7

4/22/2025FINAL

Phillies vs. Mets NL East Rivalry Renewed at Citi Field: Pitching Standouts Set to Shine in Highly Anticipated Matchup

MLB

Philadelphia 1

New York 5

4/22/2025FINAL

Cardinals set to face Braves at Truist Park with an even split in their last ten meetings

MLB

St. Louis 10

Atlanta 4

4/22/2025FINAL

Twins favored over White Sox in upcoming three-game series, but Chicago looks to pull off the upset

MLB

Chicago 2

Minnesota 4

4/22/2025FINAL

Kansas City Royals Favored to Win Against Colorado Rockies in Interleague Matchup

MLB

Colorado 3

Kansas City 4

4/22/2025FINAL

Blue Jays vs. Astros Prediction: Toronto Looks to Bounce Back Against Houston with Chris Bassitt on the Mound

MLB

Toronto 1

Houston 5

4/22/2025FINAL

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Seattle

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Toronto

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Tampa Bay

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