SportsJaw
LeaderboardToday's GamesBest BetsOdds ComparisonConsensus PicksMake Picks
Login / Sign In
Today's GamesLatest PredictionsToday’s Best BetsOdds ComparisonConsensus PicksTeam PredictionsHead-to-Head MatchupsSJ CoinsAbout SportsJawContact UsLogin / Sign In
HomeMatchupsMake PicksLeaders
SportsJaw

The social platform for sports bettors.

Explore SportsJaw

  • Today’s Picks
  • Predictions
  • Best Bets
  • Leaderboard
  • Make Picks
  • Odds Comparison
  • Consensus Picks
  • Team Predictions
  • Head-to-Head
  • Game Briefing

Picks by Sport

  • NFL Picks
  • NCAAF Picks
  • NBA Picks
  • NCAAB Picks
  • MLB Picks
  • NHL Picks

About SportsJaw

  • How It Works
  • SJ Coins
  • Terms
  • Privacy
  • Contact Us

21+. Gambling problem? Call 1-800-GAMBLER. Picks are opinions, not guarantees. Past results do not predict future outcomes.

© 2026 SportsJaw. For entertainment purposes only. SportsJaw does not accept or place wagers.

  1. Home
  2. MLB Picks
  3. St. Louis Cardinals vs San Francisco Giants
Sat 4:05 PM ET
St. Louis Cardinals logo
St. Louis
Cardinals5
A. Pallante RHP
versus
San Francisco Giants logo
San Francisco
Giants6
T. Beck RHP
Final
Team123456789T
St. Louis Cardinals1000103005
San Francisco Giants20020

San Francisco Giants Look to Extend Dominance Over St. Louis Cardinals in Final Regular Season Matchup

Game time: September 28, 2024 at 4:05 PM ET

Venue: Oracle Park — San Francisco, California

Article updated Sep 27, 10:28 PM EDT

Published by SportsJaw Editorial Team

The St. Louis Cardinals will face off against the San Francisco Giants in the second game of their final regular-season series at Oracle Park. Cardinals' RHP Andre Pallante

Game outlook

The St. Louis Cardinals will face off against the San Francisco Giants in the second game of their final regular-season series at Oracle Park. Cardinals' RHP Andre Pallante (8-8, 3.71 ERA) will make his 20th start of the season, while the Giants have yet to announce their starting pitcher. Both teams have been eliminated from postseason contention and are playing for next year. The Cardinals previously won three out of four games against the Giants in a series earlier this season. The game is set for Wednesday at 4:05 PM Eastern time. In the upcoming matchup, the Giants are the favorites with a -160 betting line that has remained unchanged.

Betting Odds

Moneyline: Cardinals +147 | Giants -160

Spread: Cardinals +1.5 (-156) | Giants -1.5 (+130)

Total: Over/Under 7 (-110)

Based on the moneyline, the implied probability that San Francisco will win straight-up is 62%.

St. Louis Cardinals

The St. Louis Cardinals four-game winning streak was ended by the Rockies in Colorado with a 10-8 loss. The Cards need one more victory to secure their 23rd winning season in the last 25 years. Reliever Ryan Fernandez struggled in the eighth inning, giving up four earned runs. Starter Kyle Gibson allowed five runs in four innings. In the game, Lars Nootbaar, Paul Goldschmidt, Pedro Pagés, and Ivan Herrera hit home runs. Before the game, the Cardinals' pitching staff had been strong, limiting opponents to three runs or less in three consecutive games. First baseman Luken Baker is on paternity leave and catcher Wilson Contreras is on the IL with a fractured middle finger. With a power ranking of 18, St. Louis is ranked 23 in offense, 18 in defense, and have a 82-78 record this season.

1
0
1
—
6
MLB · St. Louis Cardinals at San Francisco Giants

Your Picks on Cardinals vs Giants

Picks closed
Runline
Moneyline
Total

21+. Gambling problem? Call 1-800-GAMBLER. Picks are opinions, not guarantees. Past results do not predict future outcomes.

San Francisco Giants Analysis

On Wednesday, the San Francisco Giants were defeated by the Diamondbacks, ending their five-game winning streak with a score of 8-2. Mason Black, the Giants' starting pitcher, struggled and was credited with his fifth loss of the season after allowing four earned runs in just 2.2 innings. Despite left fielder Heliot Ramos contributing with two hits and an RBI, the Giants offense couldn't overcome the Diamondbacks' strong performance. Outfielder Grant McCray had a tough game, striking out four times. The Giants have been performing well offensively recently, scoring six or more runs in three of their last five games. Black attributed his rough outing to mechanical issues and too many walks. Currently, the Giants do not have any significant injuries affecting their upcoming game on Saturday. In terms of power ranking, the Giants are ranked 9th and have a record of 77-79. Their offense is ranked 17th, averaging 4.30 runs per game, while their defense is ranked 15th, giving up an average of 4.29 points per game. In their last three matchups, the Giants defeated St. Louis.

San Francisco Giants Dominate St. Louis Cardinals at Oracle Park

The St. Louis Cardinals have struggled against the San Francisco Giants in recent matchups at Oracle Park, with a record of five losses in their past six meetings. The Giants have consistently outperformed St. Louis pitching, with a batting average of .263 in their previous 10 games at home. San Francisco boasts a 53% win rate in front of their home crowd in 2024. Their recent momentum includes five wins in their last six games, including a sweep of the Kansas City Royals. The Giants' pitching staff has been particularly strong, with a 2.04 ERA and 1.09 WHIP in their last six outings. St. Louis, on the other hand, is coming off a disappointing series against the Toronto Blue Jays, where they failed to score more than three runs in each game. Based on these statistics and trends, it is advisable to wager on a San Francisco Giants victory in their upcoming game at home.

SportsJawGame Predictions
Predicted score

Unavailable for this preview

Projected winnerUnavailableConfidencelow
Pick on the Spread

Published pick: Unavailable

Pick on the Total

Published pick: Unavailable

#StLouisCardinals#SanFranciscoGiants

Share this preview

Facebook X Reddit Email
SportsJaw logo
Written by

SportsJaw Editorial Team

SportsJaw published this archived preview from its original game-day article. Its prediction and quoted lines are preserved as written.

About our editorial process

SportsJaw Cardinals vs Giants archived game preview contains historical odds and availability that may no longer be current. View history of past Cardinals vs Giants matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · St. Louis Cardinals+147 → +114Moved
  • Moneyline · San Francisco Giants-160 → -127Moved
  • Spread · St. Louis Cardinals+1.5 (-156) → +1.5 (-190)Moved
  • Spread · San Francisco Giants-1.5 (+130) → -1.5 (+165)Moved
  • Total · Over7 (-110) → 7.5 (-110)Moved
  • Total · Under7 (-110) → 7.5 (-110)Moved

ATS and O/U trends

St. Louis Cardinals
82-78 matchup record · 6-4-0 ATS · 4-6-0 O/U
Last 10 completed games on file
San Francisco Giants
77-79 matchup record · 7-3-0 ATS · 6-2-2 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2024-09-28T02:28:51.031Z). Availability may have changed; review the cited sources.

On Wednesday, the San Francisco Giants were defeated by the Diamondbacks, ending their five-game winning streak with a score of 8-2. Mason Black, the Giants' starting pitcher, struggled and was credited with his fifth loss of the season after allowing four earned runs in just 2.2 innings. Despite left fielder Heliot Ramos contributing with two hits and an RBI, the Giants offense couldn't overcome the Diamondbacks' strong performance. Outfielder Grant McCray had a tough game, striking out four times. The Giants have been performing well offensively recently, scoring six or more runs in three of their last five games. Black attributed his rough outing to mechanical issues and too many walks. Currently, the Giants do not have any significant injuries affecting their upcoming game on Saturday. In terms of power ranking, the Giants are ranked 9th and have a record of 77-79. Their offense is ranked 17th, averaging 4.30 runs per game, while their defense is ranked 15th, giving up an average of 4.29 points per game. In their last three matchups, the Giants defeated St. Louis.

Recent head-to-head

  • 2024-09-27St. Louis Cardinals 6 · San Francisco Giants 3
Final result

Matchup pick recap

San Francisco Giants defeated St. Louis Cardinals 6-5

San Francisco Giants defeated St. Louis Cardinals 6-5 on September 28, 2024, a 1-run decision in the series. San Francisco Giants' strongest period was the 4th inning, when it outscored its opponent 2-0. Against SportsJaw's recorded St. Louis Cardinals +1.5 (-190) spread, St. Louis Cardinals covered, while the 11 combined runs finished over the recorded total of 7.5.

SportsJaw editorial picks

  • Projected winnerNo published selectionUnavailable

Tipster picks

  • MiamimikeMoneyline · San Francisco Giants -160Win
  • CoolioMoneyline · San Francisco Giants -118Win
  • OddssharkMoneyline · San Francisco Giants -118Win
  • OddssharkTotal · Over 7.5 (-110)Win